Jun 26, 2023 Leave a message

Latest Research: Identification of 145 Genes Influencing Height

American Scientist published a paper in the latest issue of the journal Cell Genomics, saying that in a study on mouse and human genes, they accurately located 145 "height genes", which can regulate chondrocytes in children's growth plates and promote height growth and development.

 

The research leader, Nora Nora Lental, a paediatric endocrinologist at Boston Children's Hospital and Harvard Medical School, pointed out that it is very challenging to determine specific genes related to Human height, because height is a complex feature and is affected by genetic and environmental factors. Their research focuses on chondrocytes, as they are the main cell type involved in bone growth. These cells determine the future length and shape of each bone and "reproduce" in the tissue area called the growth plate. The growth plate is located near the end of the long bones in children and adolescents. When a person matures, these cartilage growth plates will "close" and be replaced by hard bones.

 

In the latest study, Rental's team screened 600 million mouse chondrocytes to identify genes that affect cell proliferation and maturation. They used CRISPR Genome editing technology to "knock out" candidate genes to observe what would happen when these genes were "absent" and no longer regulate chondrocytes. As a result, they discovered 145 genes that, when knocked out, triggered abnormal growth and development of mouse chondrocytes. These abnormal growth patterns are similar to some bone diseases such as bone dysplasia. Skeletal dysplasia is a group of genetic diseases that affect the development of bones, joints, and cartilage in infants. Patients typically have short stature, short limbs, and other symptoms.

 

Next, the researchers compared the 145 mouse genes with the results of the previous large-scale genetic study (genome-wide association study) on Human height. The results showed that there was significant overlap between the "hot spot" of genes related to Human height and the 145 genes controlling the growth of mouse chondrocytes. This means that researchers have now pinpointed these genes in the Human genome, which may have a greater impact on height than other genetic factors.

 

Genes Influencing Height

 

It can be seen that congenital height defects can be compensated and changed by later period. Best Height Growth capsules advocate natural growth. It can increase the rational secretion of pituitary growth factor by supplementing FV (growth promoting factor) activated cells in human body, comprehensively act on bone differentiation function and improve bone cell growth factor, promote the formation of bone and the absorption of Osteoclast, make chondrocytes proliferate and fission, and make bones grow and regenerate rapidly, so as to achieve the goal of elevation.

 

We all hope that our children can grow to their ideal height, so how can we protect their height?

 

1. Make good dietary arrangements for children

 

Three meals a day are important, and it is important to note that the ratio of breakfast, lunch, and lunch is approximately 3:4:3. Breakfast should choose nutritious foods, such as grains, egg milk, vegetables, and fruits; Lunch should ensure that the child is full, mainly consisting of vegetables, meat, grains, etc; Dinner should be small and not too greasy. You can cook some well digested Congee with light dishes. For three meals a day, it is necessary to match meat with vegetables, coarse with fine, and Healthy diet, so that children can eat well.

 

2. Pay attention to the child's digestion and absorption

 

Not only should we pay attention to our diet, but we also need to pay attention to digestion and absorption, as this is the purpose of children's nutrition supplementation. When it comes to digestion and absorption, it is necessary to mention the spleen and stomach. The main function of the spleen and stomach is to transport and transform water and grains. Most children with indigestion suffer from spleen deficiency and problems with spleen and stomach function, so the solution for today is to cultivate the spleen and stomach well.

 

You can give children some foods that help with spleen and stomach function, such as hawthorn, which can open their appetite, enhance appetite, promote digestion, and help digestion.

 

3. Supervise children to exercise more

 

Exercise can also help children grow taller. Aerobic exercises such as jogging, brisk walking, swimming, ball games, and rope skipping can not only improve a child's immune system and enhance immunity, but also stretch the upper and lower limbs, stretching the bones and stimulating them. Moreover, exercise can promote the secretion of growth hormone, and the more growth hormone there is, the more beneficial it is for a child's height development.

 

Promote Height Growth

 

Strict selection of growth supplements

 

The slow growth of the human body is mostly caused by the excessive lack of nutrition or calcium in the body. It is necessary to go to the hospital in time for relevant inspection, and then select growth supplements with clear ingredients and 100% hormone free, such as dietary supplements containing Calcium citrate, ferrous lactate, Zinc lactate, vitamin D, lysine and other ingredients. It is a common health food in clinical practice, and advocates natural nutrition, Suitable for adolescents with stunted growth and development.

 

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